Prof. Esin AKI-YALCIN, Ph.D.

URL : http://80.251.40.59/ankara.edu.tr/esinaki/
Email : esinaki@ankara.edu.tr
Tel : +90 (312) 223 69 40

Educational and Administrative Background

1974-1978: B.Sc. at Gazi University, Faculty of Pharmacy
1983: Ph.D. at Ankara University Faculty of Pharmacy Department of Pharmaceutical Chemistry
1986-1987: Assistant Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry 
1987: Associate Professor Degree
1988-1993: Associate Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry
1993-Present: Full Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry
1999-2002: Ankara University, Faculty of Pharmacy, Head of the Department of Pharmaceutical Chemistry
2003-2006: Ankara University, Faculty of Pharmacy, Chair of Pharmaceutical Sciences Division
2007-Present: President of the Computer Aided Drug Design and Development Society in Turkey
2008-2012: Assistant to the President of Ankara University

Language Background

  •  Turkish (Native Language)
  •  English (Fluent)
  •  Spanish (Beginner Level)

Doctoral Theses Supervised

  •  Ozlem TEMIZ, 1998, “Synthesis, Structure Elucidation, Microbiological Activity and Quantitative Structure-Activity Relationship Analysis of 5-(2-Furylcarboxamido)-, 5-(2-Thienylcarboxamido)-, 5-Benzamido- and 5-phenylacetamido- 2-phenylbenzoxazole Derivatives” 
  •  Sabiha ALPER-HAYTA, 2009, "Synthesis, Structure Elucidation, Antimicrobial Activity and Molecular Modelling Studies of Novel Benzoxazole compounds"

Master Theses Supervised

  •  Hulya TURGUT, 1989, “Synthesis, Structure Elucidation and Microbiological Activity of 5-Substituted-2-(3-pyridyl)benzoxazole Derivatives”
  •  Ozlem TEMIZ, 1991, “Synthesis, Structure Elucidation and Microbiological Activity of 5-Methyl-2-(p-substitutedbenzyl)benzoxazole Derivatives “
  •  Cengiz ERTAS, 1998, “Studies on Synthesis, Structure Elucidation and Microbiological Activity of Possible Metabolites of Benzoxazoles, 4-Substituted-N-(2-hydroxy-5-nitrophenyl)benzamide ve Benzene-acetamide Derivatives” 
  •  Kamuran Kadri BINGOL, 1994, “Studies on Synthesis and Microbiological Activity of Possible Metabolites of Benzoxazoles”
  •  Sabiha ALPER, 2002, “Studies on Synthesis, Structure Elucidation and Microbiological Activity of Ethyl-3,4-dihydro-6- and/or 7-substituted-3-oxo-2H-1,4-benzoxazine-2-acetate ve ethyl 3,4- dihydro -N(4)-methyl-6- and/or 7-substituted-3-oxo-2H-1,4-benzoxazine-2-acetate”
  •  Murat YILMAZ, 2004, “Oral Antidiabetic Drugs”

Editorial Board Memberships

  •  ARKIVOC Journal
  •  Current Computer Aided Drug Design Journal
  •  Journal of Faculty of Pharmacy of Ankara University

Symposium and Meeting Organizations

  •  Chair of the “15th European Symposium on Quantitative Structure-Activity Relationships”, Istanbul, September 05-10, 2004.
  •  Chair of the Organizing Committee of the "Workshop on Computer Aided Drug Design & Development", Istanbul-TURKEY, February 02-05, 2007.
  •  Chair of the Organizing Committee of the “6th AFMC International Medicinal Chemistry Symposium", Istanbul-TURKEY, July 01-04, 2007.

Memberships

  •  International QSAR and Modelling Society
  •  American Chemical Society
  •  Ankara University Alumni Association
  •  Turkish Association of Pharmaceutical and Medicinal Chemistry 
  •  Computer Aided Drug Design and Development Society (CADD&D Society) in Turkey
  •  The Society of Pharmaceutical Sciences of Ankara (FABAD)
  •  Development Association of Ankara University, Faculty of Pharmacy

Artículos Científicos

  • 80
    ZILIFDAR, F., ALPER-HAYTA, S., YILMAZ, S., KAPLAN-OZEN, C., FOTO, E., AYDOGAN, Z., YILDIZ, I., AKI, E., YALCIN, I., DIRIL, N., "Genotoxic potentials and eukaryotic DNA topoisomerase I inhibitory effects of some benzoxazine derivatives", Med. Chem. Res., 23(1), 480-486, (2014). DOI: 10.1007/s00044-013-0658-5 [texto íntegro]
  • 79
    YILMAZ, S., YALCIN, I., KAYNAK-ONURDAG, F., OZGEN, S., YILDIZ, I., and AKI, E., "Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles", Croat. Chem. Acta, 86(2), 223-231, (2013). Doi: 10.5562/cca2064 [texto íntegro]
  • 78
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., YILMAZ, S., YILDIZ, I., AKI, E., "Quantum mechanical and spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations of 2-(p-nitrobenzyl) benzoxazole", Journal of Molecular Structure, 1046, 92-100, (2013). Doi: 10.1016/j.molstruc.2013.04.044 [texto íntegro]
  • 77
    KAPLAN-OZEN, C., TEKINER-GULBAS, B., FOTO, E., YILDIZ, I., DIRIL, N., AKI, E., YALCIN, I., "Benzothiazole derivatives as human DNA topoizomerase IIα inhibitors", Med. Chem. Res., 22(12), 5798-5808, (2013). DOI: 10.1007/s00044-013-0577-5 [texto íntegro]
  • 76
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., BOLELLI, K., YILDIZ, I., AKI, E., "Vibrational spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations and computational study of 5-nitro-2-(4-nitrobenzyl) benzoxazole", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 102, 99-113, (2013). doi:10.1016/j.saa.2012.09.032 [texto íntegro]
  • 75
    BOLELLI, K., YALCIN, I., ERTAN-BOLELLI, T., OZGEN, S., KAYNAK-ONURDAG, F., YILDIZ, I, AKI, E., "Synthesis of novel 2-[4-(4-substitutedbenzamido/phenylacetamido)phenyl]benzothiazoles as antimicrobial agents", Med. Chem. Res., 21, 3818-3825, (2012). DOI: 10.1007/s00044-011-9918-4 [texto íntegro]
  • 74
    TASKIN, T., YILMAZ, S., YILDIZ, I., YALCIN, I., AKI, E., "Insight into eukaryotic topoisomerase II-inhibiting fused heterocyclic compounds in human cancer cell lines by molecular docking", SAR and QSAR Environmental Research, 23(3-4), 345-355, (2012). Doi:10.1080/1062936X.2012.664560 [texto íntegro]
  • 73
    KAROLAK-WOJCIECHOWSKA, J., SZCZESIO, M., ERTAN-BOLELLI, T., AKI, E., YALÇIN, I., "Crystal structure of 4-fluoro-N-(2-hydroxy-4-nitrophenyl)benzamide, C13H9FN2O4", Z. Kristallogr. NCS, 225, 533-534, (2010). DOI: 10.1524/ncrs.2010.0234 [texto íntegro]
  • 72
    KAROLAK-WOJCIECHOWSKA, J., SZCZESIO, M., ALPER-HAYTA, S., AKI, E., YALÇIN, I., "Crystal structure of 3,4-dihydro-3-oxo-6-ethoxycarbonyl-2H-1,4-benzoxazine-2-acetate, C15H17NO6", Z. Kristallogr. NCS, 225, 531-532, (2010). DOI: 10.1524/ncrs.2010.0233 [texto íntegro]
  • 71
    FILAK, F., TEKINER-GULBAS, B., RIEDL, Z., VASKO, G.A., EGYED, O., YALÇIN, I., AKI-SENER, E., HAJOS, G., “Ring Expansion of N-Aminobenzothiazolium Salts to Benzothiazines and Benzothiadiazines”, Acta Chim. Slov, 56, 622–628, (2009). WOS:000270787600013 [texto íntegro]
  • 70
    ZEYBEK, B., DURMUŞ, Z., TEKİNER-GÜLBAŞ, B., AKI-ŞENER, E., YALÇIN, İ., KILIÇ, E., "Electrochemical Behaviors and Determinations of Some 2,5-Disubstituted Benzoxazole Compounds at the Hanging Mercury Drop Electrode", Current Pharmaceutical Analysis, 5, 21-27, (2009). WOS:000263953500003 [texto íntegro]
  • 69
    ERTAN, T., YILDIZ, I., TEKINER-GULBAS, B., BOLELLI, K., TEMIZ-ARPACI, O., OZKAN, S., KAYNAK, F., YALCIN, I., AKI, E., “Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents”, European Journal of Medicinal Chemistry, 44, 501–510, (2009). doi:10.1016/j.ejmech.2008.04.001 [texto íntegro]
  • 68
    TEMIZ-ARPACI, Ö., YILDIZ, I., OZKAN, S., KAYNAK, F., AKI-SENER, E., YALÇIN, I., "Synthesis and biological activity of some new benzoxazoles" European Journal of Medicinal Chemistry, 43, 1423-1431, (2008). doi:10.1016/j.ejmech.2007.09.023 [texto íntegro]
  • 67
    TEKINER-GULBAS, B., FILAK, F., VASKO, G.A., EGYED, O., YALÇIN, I., AKI-SENER, E., RIEDL, Z., HAJOS, G.,“Synthesis of Novel Pyrazolo[5,1-b][1,3]benzothiazoles: A New Pericyclic Pathway”, Heterocycles, 75(8), 2005–2012, (2008). WOS:000259131300011 [texto íntegro]
  • 66
    ARISOY, M., TEMIZ-ARPACI, O., YILDIZ, I., KAYNAK-ONURDAG, F., AKI, E., YALCIN, I., ABBASOGLU, U., “Synthesis, Antimicrobial Activity and QSAR Studies of 2,5-Disubstituted Benzoxazoles”, SAR and QSAR in Environmental Research, 19(5–6), 589–612, (2008). DOI: 10.1080/10629360802348738 [texto íntegro]
  • 65
    YILDIZ, I., ERTAN, T., BOLELLI, K., TEMIZ-ARPACI, O.,YALCIN, I. AKI, E., "QSAR and Pharmacophore Analysis on Amides against Drug-Resistant S. aureus", SAR and QSAR in Environmental Research, 19(1-2), 101-113, (2008). DOI: 10.1080/10629360701844159 [texto íntegro]
  • 64
    ALPER-HAYTA, S., ARISOY, M., TEMIZ-ARPACI, Ö., YILDIZ, I., AKI, E., ÖZKAN, S., KAYNAK, F., "Synthesis, Antimicrobial Activity, Pharmacophore Analysis of Some New 2-(Substitutedphenyl/ benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles", European Journal of Medicinal Chemistry, 43(11), 2568-2578, (2008). doi:10.1016/j.ejmech.2007.12.019 [texto íntegro]
  • 63
    OKSUZOGLU, E., TEKINER-GULBAS, B., ALPER, S., TEMIZ-ARPACI, O., ERTAN, T., YILDIZ, I., DIRIL, N., SENER-AKI, E., YALCIN, I., "Some Benzoxazoles and Benzimidazoles as DNA Topoisomerase I and II Inhibitors", Journal of Enzyme Inhibition and Medicinal Chemistry, 23(1), 37-42, (2008). DOI: 10.1080/14756360701342516 [texto íntegro]
  • 62
    OKSUZOGLU, E., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., EROGLU, H., SEN, G., ALPER, S., YILDIZ, I., DIRIL, N., AKI-SENER, E., YALCIN, I., "A Study on the Genotoxic Activities of Some New Benzoxazoles", Medicinal Chemistry Research, 16, 1–14, (2007). DOI 10.1007/s00044-007-9005-z [texto íntegro]
  • 61
    TEKINER-GULBAS, B., TEMIZ-ARPACI, O., OKSUZOGLU, E., EROGLU, H., YILDIZ, I., DIRIL, N., AKI-SENER, E., YALCIN, I., "QSAR of Genotoxic Active Benzazoles", SAR and QSAR in Environmental Research, 18(3-4), 251–263, (2007). DOI: 10.1080/10629360701303966 [texto íntegro]
  • 60
    MARTINS, M., SCHELZ, Z., MARTINS, A., MOLNAR, J., HAJÖS, G., RIEDL, Z., VIVEIROS, M., YALCIN, I., AKI-SENER, E., AMARAL, L., "In Vitro and Ex Vivo Activity of Thioridazine Derivatives against Mycobacterium tuberculosis", International Journal of Antimicrobial Agents, 29, 338–340, (2007). doi:10.1016/j.ijantimicag.2006.10.013 [texto íntegro]
  • 59
    ERTAN, T., YILDIZ, I., OZKAN, S., TEMIZ-ARPACI, O., KAYNAK, F., YALCIN, I., AKI-SENER, E., ABBASOGLU, U., "Synthesis and Biological Evaluation of New n-(2-Hydroxy-4(or 5)-nitro/ aminophenyl)benzamides and Phenylacetamides as Antimicrobial Agents", Bioorganic and Medicinal Chemistry, 15, 2032-2044, (2007). doi:10.1016/j.bmc.2006.12.035 [texto íntegro]
  • 58
    KAROLAK-WOJCIECHOWSKA, J., MROZEK, A., CZYLKOWSKI, R., TEKINER-GULBAS, B., AKI-SENER, E., YALCIN, I., "Five-membered heterocycles. Part IV: Impact of heteroatom on benzazole aromaticity", Journal of Molecular Structure, 839, 125-131, (2007). doi:10.1016/j.molstruc.2006.11.023 [texto íntegro]
  • 57
    TEMİZ-ARPACI, Ö., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALCIN, İ., "3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method", QSAR and Molecular Modelling in Rational Design of Bioactive Molecules, Istanbul-Turkey, September 5-10, 2004, AKI-ŞENER, E., YALÇIN, İ. (Eds.), Başkent Publishing, Ankara, pp.396-398, (2006). [texto íntegro]
  • 56
    ALPER-HAYTA, S., AKI-SENER, E., TEKINER-GULBAS, B., YILDIZ, I., TEMIZ-ARPACI, O., YALCIN, I., ALTANLAR, N., “Synthesis, Antimicrobial Activity and QSARs of New Benzoxazine-3-ones”, Eur. J. Med. Chem., 41(12), 1398-1404, (2006). [texto íntegro]
  • 55
    TEMIZ-ARPACI, O., COBAN, T., TEKINER-GULBAS, B., CAN-EKE, B., YILDIZ, İ., AKI-SENER, E., YALCIN, I., ISCAN, M., “A Study on the Antioxidant Activities of Some New Benzazole Derivatives”, Acta Biol. Hungarica, 57(2), 201-209, (2006). [texto íntegro]
  • 54
    TEKINER-GULBAS, B., TEMIZ-ARPACI, O., YILDIZ, I., AKI-SENER, E., YALCIN, I., “3D-QSAR Study on Heterocyclic Topoisomerase II Inhibitors using CoMSIA”, SAR and QSAR in Enviromental Research, 17(2), 121-132, (2006). [texto íntegro]
  • 53
    LAGE, H., AKI-SENER, E., YALCIN, I., “High Antineoplastic Activity of New Heterocyclic Compounds in Cancer Cells with Resistance against Classical DNA Topoisomerase II Targeting Drugs”, Int. J. Cancer, 119, 213-220, (2006). [texto íntegro]
  • 52
    VARGA, A., AKI-SENER, E., YALCIN, I., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., CHEREPNEV, G., MOLNAR, J., “Induction of Apoptosis and Necrosis by Resistance Modifiers Benzazoles and Benzoxazines on Tumour Cell Line Mouse Lymphoma L5718 Mdr+cells”, In vivo, 19, 1087-1092, (2005). [texto íntegro]
  • 51
    TEMIZ-ARPACI, O., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALÇIN, İ., “3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method”, Bioorganic&Medicinal Chemistry, 13, 6354–6359, (2005). [texto íntegro]
  • 50
    TEMİZ-ARPACI, O., ÖZDEMİR, A., YALÇIN, İ., YILDIZ, İ., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some 5-[2-(Morpholin-4-yl)acetamido] and/or 5-[2-(4-Substituted piperazin-1-yl)acetamido]-2-(p-substituted phenyl)benzoxazoles", Arch. Pharm. Chem. Life Sci., 338, 105-111, (2005). [texto íntegro]
  • 49
    YILDIZ-OREN, İ., TEKINER-GULBAŞ, B., TEMİZ-ARPACI, Ö., YALÇIN, İ., AKI-SENER, E., "Quantitative Structure-Activity Relationships using Comparative Molecular Field Analysis Studies on 2-(p-Substitutedbenzyl)-5-(substituted carbonylamino)benzaoxazoles as Antibacterial Agents against Staphylococcus aureus", Asian Journal of Chemistry, 16(3-4), 1359-1366, (2004). [texto íntegro]
  • 48
    ÖREN-YILDIZ, İ., TEKİNER-GULBAŞ, B., YALÇIN, İ., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of New 2-[p-Substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles”, Arch. Pharm. Pharm. Med. Chem, 337, 402-410, (2004). [texto íntegro]
  • 47
    PLEMPER, R.K., ERLANDSON, K.J., LAKDAWALA, A.S., SUN, A., PRUSSIA, A., BOONSOMBAT, J., AKI-ŞENER, E., YALÇIN, İ., YILDIZ, İ., TEMİZ-ARPACI, Ö., TEKİNER, B. P., LIOTTA, D., SNYDER, J.P., COMPANS, R.W., “A Target Site for Template-Based Design of Measles Virus Entry Inhibitors”, PNAS, 101(15), 5628-5633, (2004). [texto íntegro]
  • 46
    ÖREN-YILDIZ, İ., YALÇIN, İ., AKI-ŞENER, E., UCARTURK, N., “Synthesis and Structure-Activity Relationships of New Antimicrobial Active Multisubstituted Benzazole Derivatives”, European Journal of Medicinal Chemistry, 39, 291-298, (2004). [texto íntegro]
  • 45
    PINAR, A., YURDAKUL, P., YILDIZ, İ., TEMİZ-ARPACI, Ö., AÇAN, N.L., AKI-ŞENER, E., YALÇIN, İ.,”Some Fused Heterocyclic Compounds as Eukaryotic Topoisomerase II Inhibitors”, Biochemical and Biophysical Research Communications, 317, 670-674, (2004). [texto íntegro]
  • 44
    YILDIZ-ÖREN, i., AKI-ŞENER, E., ERTAŞ, C., TEMİZ-ARPACI, Ö., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological activity of Some Substituted N-(2-hydroxy-4-nitrophenyl)benzamides and phenylacetamides as Possible Metabolites of Antimicrobial Active Benzoxazoles”, Turk J Chem., 28, 441-449, (2004). [texto íntegro]
  • 43
    YALÇIN, İ., TEKİNER, B.P., ÖREN-YILDIZ, İ., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some Novel 2,6,7-trisubstituted-2H-3,4-dihydro-1,4-benzoxazin-3-one Derivatives”, Indian Journal of Chemistry, 42B, 905-909, (2003). [texto íntegro]
  • 42
    AKBAY, A., ÖREN, İ., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., YALÇIN, İ., “Synthesis and HIV-1 Reverse Transcriptase Inhibitor Activity of Some 2,5,6-Substituted Benzoxazole, Benzimidazole, Benzothiazole and Oxazolo(4,5-b)pyridine Derivatives”, Arzneim-Forsch./Drug Res., 53(4), 266-271, (2003). [texto íntegro]
  • 41
    AKBAY-YARPUZLU, A., YILDIZ, İ., TEMIZ-ARPACI, Ö., KARAGENÇ, N., AKI-ŞENER, E., YALÇIN, İ., “Adenosine Deaminase Inhibitor Activity of Some Benzoxazole, Benzimidazole, and Oxazolo(4,5-b)pyridine Derivatives”, XIII. Biotecnological Congress Proceedings Book, Çanakkale, 21-26, (2003).
  • 40
    TEMIZ-ARPACI, Ö., OREN, İ., AKI-ŞENER, E., YALÇIN, İ., TEKINER, B., “QSARs of Some Antibacterial Active Benzoxazoles against B. subtilis”, J. Fac. Pharm., Ankara, 31(2), 73-81, (2002). [texto íntegro]
  • 39
    TEMİZ-ARPACI, Ö., AKI-ŞENER, E., YALÇIN, İ., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some 2-(p-Substituted-phenyl)benzoxazol-5-yl-arylcarboxamides”, Arch. Pharm. Pharm. Med. Chem, 6, 283-288, (2002). [texto íntegro]
  • 38
    TEMİZ-ARPACI, Ö., AKI-ŞENER, E., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological Activity of Some Novel N-[2-(p-Substitutedphenyl)-5-benzoxazolyl]-cyclohexyl carboxamide, -cyclohexyl acetamide and –cyclohexyl propionamide Derivatives”, Il Farmaco, 57, 771-775, (2002). [texto íntegro]
  • 37
    AKI-ŞENER, E., BİNGÖL, K.K., TEMİZ-ARPACI, Ö., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological Activity of Some N-(2-hydroxy-4-substitutedphenyl)benzamides, phenylacetamides and furamides as the Possible Metabolites of Antimicrobial Active Benzoxazoles”, Il Farmaco, 57, 451-456, (2002). [texto íntegro]
  • 36
    CZYLKOWSKI, R., KAROLAK-WOJCIECHOWSKA, J., MROZEK, A., YALÇIN, İ., ŞENER, E.A., “Spacer Conformation in Biologically Active Molecules. Part I. Structure and Conformational Preferences of 2-Substituted-benzoxazoles”, J. Mol. Structure, 598(2-3), 197-204, (2001). [texto íntegro]
  • 35
    AKI-ŞENER, E., BİNGÖL, K.K., ÖREN, İ., TEMİZ-ARPACI, Ö., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological Activity of Some N-(o-hydroxyphenyl)benzamides and phenylacetamides as the Possible Metabolites of Antimicrobial Active Benzoxazoles, Part II.”, Il Farmaco, 55, 469-476, (2000). [texto íntegro]
  • 34
    YALÇIN, İ., ÖREN, İ., TEMİZ, Ö., ŞENER, E.A., “QSARs of Some Novel Isosteric Heterocyclics with Antifungal Activity”, Acta Biochimica Polonica, 47(2), 481-486, (2000). [texto íntegro]
  • 33
    AKI-ŞENER, E., ARPACI-TEMİZ, Ö., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological Activity of Some Novel 5-Benzamido- and 5-phenylacetamido- substituted 2-phenylbenzoxazole Derivatives”, Il Farmaco, 55, 397-405, (2000). [texto íntegro]
  • 32
    MROZEK, A., TRZEZWINSKA, H., KAROLAK-WOICIECHOWSKA, J., YALÇIN, İ., ŞENER, E., “Molecular Structure of 5-Chloro-2-(p-t-butylphenyl)benzoxazole. Relation Between Structure and Antimicrobial Activity of 2,5-Disubstituted Benzoxazoles”, Polish J. Chem., 73, 625-633, (1999). [texto íntegro]
  • 31
    MROZEK, A., KAROLAK-WOICIECHOWSKA, J., YALÇIN, İ., ŞENER, E., “Crystal Structure of 2-(2'-Cyclohexyl)ethyl benzimidazole, C15H20N2”, Z. Kristallogr. NCS, 214, 181-182, (1999). [texto íntegro]
  • 30
    ÖREN, İ., TEMİZ, Ö., YALÇIN, İ., ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some Novel 2, 5- and/or 6-Substituted Benzoxazole and Benzimidazole Derivatives”, European Journal of Pharmaceutical Sciences, 7(2), 153-160, (1999). [texto íntegro]
  • 29
    TEMİZ, Ö., ÖREN, İ., ŞENER, E., YALÇIN, İ., UÇARTÜRK, N., “Synthesis and Microbiological Activity of Some Novel 5- or 6-Methyl-2-(2,4-disubstituted phenyl)benzoxazole Derivatives”, Il Farmaco, 53, 337-341, (1998). [texto íntegro]
  • 28
    YALÇIN, İ., KAYMAKÇIOĞLU, B.K., ÖREN, İ., ŞENER, E., TEMİZ, Ö., AKIN, A., ALTANLAR, N., “Synthesis and Microbiological Activity of Some Novel N-(2-Hydroxyl-5-substitutedphenyl)benzacetamides, Phenoxyacetamides and Thiophenoxyacetamides as The Possible Metabolites of Antimicrobial Active Benzoxazoles”, Il Farmaco, 52(11), 685-689, (1997). [texto íntegro]
  • 27
    ÖREN, İ., TEMİZ, Ö., YALÇIN, İ., ŞENER, E., AKIN, A., UÇARTÜRK, N., “Synthesis and Microbiological Activity of 5(or 6)-Methyl-2-substituted Benzoxazole and Benzimidazole Derivatives”, Arzneim-Forsch./Drug Res., 47(II), 1393-1397, (1997). [texto íntegro]
  • 26
    ŞENER, E., YALÇIN, İ., TEMİZ, Ö., ÖREN, İ., AKIN, A., UÇARTÜRK, N., "Synthesis and Structure-Activity Relationships of Some 2,5-Disubstitured Benzoxazoles and Benzimidazoles as Antimicrobial Agents", Il Farmaco, 52(2), 99-103, (1997). [texto íntegro]
  • 25
    TÜRKER, L., GÜLLÜ, M., YALÇIN, İ., ŞENER, E., ÇELEBİ, N., "Relationships Between Theoretically Calculated LUMO Energies and Cathodic Peak Potentials of Some 2-Benzylbenzoxazole Derivatives", Bulletin Soc Chim. Belg, 105(6), 303-306, (1996). [texto íntegro]
  • 24
    ŞENER, E., TEMİZ, Ö., ÖREN, İ., YALÇIN, İ., AKIN, A., UÇARTÜRK, N., "Synthesis, Antibacterial Activity and QSARs of Some 5-Substituted-2-(p-substitutedbenzyl)benzoxazoles using the Free-Wilson Analysis", J. Fac. Pharm. Ankara, 24(1), 10-20, (1995). [texto íntegro]
  • 23
    YALÇIN, İ., ŞENER, E., ÖREN, İ., TEMİZ, Ö., "Determination of the Activity Contributions of Some Novel Isosteric Heterocyclics against an Enteric Gram-negative Rod using the Free-Wilson Analysis" In Sans, F., Giraldo, J. and Manaut, F. (Eds.) QSAR and Molecular Modelling:Concepts, Computational Tools and Biological Applications. Prous, Barcelona, pp. 147-151 (1995).
  • 22
    GÜLLÜ, M., YALÇIN, İ., ŞENER, E., TÜRKER, L., ÇELEBİ, N., AKBULUT, U., "Relationships between Cathodic Peak Potentials and Theoretically Calculated LUMO Energies of Some 2-Phenybenzoxazole Derivatives", Bulletin Soc. Chim. Belg, 103(3), 87-90, (1994). [texto íntegro]
  • 21
    ŞENER, E., TURGUT, H., YALÇIN, İ., ÖREN, İ., TÜRKER, L., ÇELEBİ, N., AKIN, A., "Synthesis, Microbiological Activity and Structure-Activity Relationships of Some Antimicrobial 5-Substituted-2-(3-pyridyl)benzoxazoles using Quantum Chemical Calculations", International Journal of Pharmaceutics, 110, 109-115, (1994). [texto íntegro]
  • 20
    YALÇIN, İ., ŞENER, E., ÖREN, İ., "QSAR of Some Antibacterial Active Isosteric Heterocyclic Compounds against an Enterobacter" In Wermuth, C. G. (Ed.) Trends in QSAR and Molecular Modelling 92. Escom, Leiden, pp. 570-572 (1993).
  • 19
    YALÇIN, İ., ŞENER, E., "QSARs of Some Novel Antibacterial Benzimidazoles, Benzoxazoles and Oxazolopyridines against an Enteric Gram-negative Rod K. pneumoniae", International Journal of Pharmaceutics, 98, 1-8, (1993). [texto íntegro]
  • 18
    YALÇIN, İ., ÖREN, İ., ŞENER, E., AKIN, A., UÇARTÜRK, N., "The Synthesis and the Structure- Activity Relationships of Some Substituted Benzoxazoles, Oxazolo(4,5-b)pyridines, benzothiazoles and benzimidazoles as Antimicrobial Agents", European Journal of Medicinal Chemistry, 27, 401-406, (1992). [texto íntegro]
  • 17
    TÜRKER, L., ŞENER, E., YALÇIN, İ., AKBULUT, U., KAYALIDERE, İ., "QSAR of Some Antifungal Active Benzoxazoles using the Quantum Chemical Parameters", Scientica Pharmaceutica, 58, 107-113, (1990). [texto íntegro]
  • 16
    YALÇIN, İ., ŞENER, E., ÖZDEN, T., ÖZDEN, S., AKIN, A., "Synthesis and Microbiological Activity of 5-Metyl-2-(p-substitutedphenyl)benzoxazoles", European Journal of Medicinal Chemistry, 25, 705-708, (1990). [texto íntegro]
  • 15
    YALÇIN, İ., ŞENER, E., ÖZDEN, S., ÖZDEN, T., AKIN, A., YILDIZ, S., "The Antibacterial Activity of 2-Phenyloxazolo(4,5-b)pyridine Derivatives against Gram(-) Bacteria and the Quantitative Structure-Activity Relationships", FABAD J. Pharm. Sci., 13(3), 441-449, (1988). [texto íntegro]
  • 14
    ŞENER, E., YALÇIN, İ., AKIN, A., NOYANALPAN, N., "Antifungal Activity of 2-Benzylbenzoxazole Derivatives and QSAR’s by Free-Wilson Analysis", J. Fac. Pharm. Gazi, 4(1), 1-9, (1987). [texto íntegro]
  • 13
    ŞENER, E., YALÇIN, İ., ÖZDEN, S., ÖZDEN, T., AKIN, A., YILDIZ, S., "Synthesis and Antimicrobial Activities of 5-Amino-2-(p-substitutedphenyl)benzoxazole Derivativies", Doğa TUJ. Med. and Pharm., 11(3), 391-396, (1987). [texto íntegro]
  • 12
    ŞENER, E., YALÇIN, İ., ÖZDEN, S., ÖZDEN, T., AKIN, A., YILDIZ, S., "The Antifungal Activity of 2-(p-Substitutedphenyl)oxazolo(4,5-b)pyridine Derivatives against Candida albicans and the Quantitative Structure-Activity Relationships", FABAD J. Pharm. Sci., 12(4), 281-288, (1987). [texto íntegro]
  • 11
    YALÇIN, İ., ŞENER, E., ÖZDEN, S., ÖZDEN, T., "The Quantitative Structure-Activity Relationships of Antibacterial Active 2-(p-Substitutedphenyl)benzoxazole Derivatives against Gram (+) Bacteria using the Combinations of Some Hydrophobic, Electronic and Steric Paramaters", FABAD J. Pharm. Sci., 12(1), 48-55, (1987). [texto íntegro]
  • 10
    YALÇIN, İ., ŞENER, E., ÖZDEN, S., AKIN, A., YILDIZ, S., "The Antibacterial Activity of 2-(p-Substitutedphenyl)oxazolo(4,5-b)pyridine Derivatives against Streptococcus faecalis and Staphylococcus aureus and the Quantitative Structure-Activity Relationships", FABAD j. Pharm. Sci., 12(3), 213-221, (1987). [in Turkish] [texto íntegro]
  • 9
    ÖZDEN, S., ÖZDEN, T., ŞENER, E., YALÇIN, İ., AKIN, A., YILDIZ, S., "The Synthesis, Structure Elucidations and Microbiological Activities of 5-Nitro-2-(p-Substitutedphenyl)benzoxazoles-III", FABAD J. Pharm. Sci., 12(1), 39-47, (1987). [in Turkish] [texto íntegro]
  • 8
    ŞENER, E., YALÇIN, İ., ÖZDEN, S., ÖZDEN, T., "The Quantitative Structure-Activity Relationships of Antibacterial Active 2-(p-Substitutedphenyl)benzoxazole Derivatives against Gram (-) Bacteria using the Combinations of Some Hydrophobic, Electronic and Steric Paramaters", J. Fac. Pharm. Gazi, 3(2), 133-142, (1986). [texto íntegro]
  • 7
    NOYANALPAN, N., ŞENER, E., "The Quantitative Structure-Activity Relationships of AntiHistaminic Active 5-Substituted-2-(p-Substitutedbenzyl)benzoxazole Derivatives", J. Fac. Pharm. Gazi, 3(1), 1-11, (1986). [texto íntegro]
  • 6
    ŞENER, E., YALÇIN, İ., ÖZDEN, S., ÖZDEN, T., "The Quantitative Structure-Activity Relationships of Antifungal Active 2-(p-Substitutedphenyl)benzoxazole Derivatives against Candida albicans using the Combinations of Some Hydrophobic, Electronic and Steric Paramaters", J. Fac. Pharm. Ankara, 16(1), 24-30, (1986) [texto íntegro]
  • 5
    YALÇIN, İ., ŞENER, E., ÖZDEN, T., ÖZDEN, S., AKIN, A., YILDIZ, S., "The Synthesis, Structure Elucidations and Microbiological Activities of 5-Chloro-2-(p-Substitutedphenyl)benzoxazoles-II", FABAD J. Pharm. Sci., 11(4), 257-269, (1986). [in Turkish] [texto íntegro]
  • 4
    ŞENER, E., ÖZDEN, S., YALÇIN, İ., ÖZDEN, T., AKIN, A., YILDIZ, S., "The Synthesis, Structure Elucidations and Microbiological Activities of 2-(p-Substitutedphenyl)benzoxazoles-I", FABAD J. Pharm. Sci., 11(3), 190-202, (1986). [in Turkish] [texto íntegro]
  • 3
    NOYANALPAN, N., ŞENER, E., "The Synthesis, Structure Elucidations and Antihistaminic Activities of 5-Nitro-2-(p-substitutedbenzyl)benzoxazole Derivatives", FABAD J. Pharm. Sci., 11(2), 111-119, (1986). [in Turkish] [texto íntegro]
  • 2
    YALÇIN, İ., ŞENER, E., ÖZDEN, T., "The Synthesis and Structure Elucidations of 2-(p-Substitutedphenyl)oxazolo(4,5-b)pyridine Derivatives", J. Fac. Pharm. Ankara, 15(1), 69-78, (1985). [in Turkish] [texto íntegro]
  • 1
    NOYANALPAN, N., ŞENER, E., "The Synthesis, Structure Elucidations and Antihistaminic Activities of 2-(p-Substitutedbenzyl)benzoxazole Derivatives", FABAD J. Pharm. Sci., 10(4), 275-286, (1985). [in Turkish] [texto íntegro]

Patentes

  • 1
    KIESSIG STEPHAN [DE]; ROCKENSUESS KLAUS-DIETER [DE]; VARGA ANDRAS [DE]; MOLNAR JOSEF [HU]; CHEREPNEV GEORGY [RU]; AKI ESIN [TR]; YALCIN ISMAIL [TR]; LAGE HERMANN [DE]; AMARAL LEONARD [US]; "Composition, useful e.g. for the chemosensibilizing and simultaneous apoptosis induction of multidrug resistance of tumor cells and bacteria, comprises substituted disiloxane compound in combination with benzoxazole derivatives"; DE102008027361; [fulltext] [patent page]

Artículos de Revisión

  • 8
    ALPER, S., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., YALÇIN, İ.,”Some New bi-and ter-benzimidazole Derivatives as Topoisomerase I Inhibitors”, Il Farmaco, 58, 497-507, (2003). [texto íntegro]
  • 7
    YALÇIN, İ., ŞENER, E., "Türkiye İlaç Endüstrisinde Özgün İlaç Etken Maddesi Tasarım ve Geliştirilmesi Çalışmalarının Önem ve Gereksinimi", İlaç ve Kimya Endüstrisi İşverenler Sendikası Yayını, 99-100-101, 4-5, (1996). [in Turkish]
  • 6
    TEMİZ, Ö., ŞENER, E., "Newly Developed Benzodiazepine Derivatives and Their Biological Activites", J. Fac. Pharm. Ankara, 23(1-2), 37-52, (1994). [in Turkish] [texto íntegro]
  • 5
    TEMİZ, Ö., ŞENER, E., "The Microbiological Activity of Benzoxazole, Benzimidazole and Oxazolo(4,5-b)pyridine Derivatives", J. Fac. Pharm. Ankara, 21(1-2), 36-52, (1992). [in Turkish] [texto íntegro]
  • 4
    YALÇIN, İ., ŞENER, E., "The Studies on the Searching and Developing of Antiinflammatory, Analgesic and Antipiretic Active Quinazolinon Derivatives", Bulletin of Ankara Chamber of Pharmacists, 8(4), 269-276, (1986). [in Turkish] [texto íntegro]
  • 3
    ŞENER, E., YALÇIN, İ., "The Role of Histamine in Inflammation, Activity of the Antiinflammatory Compounds against Histamine", Bulletin of Ankara Chamber of Pharmacists, 8(2),99-110, (1986). [in Turkish] [texto íntegro]
  • 2
    YALÇIN, İ., ŞENER, E., "The Structure-Activity Relationships of Selective Antiinflammatory Active Nonacidic Polyaryl Heterocyclic Compounds", FABAD J. Pharm. Sci., 10(3), 183-194, (1985). [in Turkish] [texto íntegro]
  • 1
    BÜYÜKBINGÖL, E., ŞENER, E., "The Meaning of Structure-Activity Relationships in the Medicinal Chemistry Concept", Pharmacia-JTPA, 24: 52(2), 126-133, (1984). [in Turkish] [texto íntegro]

Presentaciones Orales

  • 20
    YILDIZ, I., ALPER, S., ERTAN, T., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., AKI-SENER, E., YALCIN, I., "Molecular Modeling Studies on Some Eucaryotic Topoisomerase II Enzyme Inhibitor Fused Heterocyclic Compounds", 6th AFMC International Medicinal Chemistry Symposium, Istanbul-TURKEY, July 08-11, 2007.
  • 19
    PINAR, A., YURDAKUL, P., TEMİZ-ARPACI, O., TEKİNER-GÜLBAŞ, B., YILDIZ, I., AKI-ŞENER, E., YALÇIN, İ., İLERİ, O., “Eukaryotic Topoisomerase II activity of some novel fused heterocyclic compounds”, 31st FEBS Congress, İstanbul, Turkey, 24-29 June 2006.
  • 18
    TEMİZ ARPACI, Ö., ÖKSÜZOĞLU, e., TEKİNER-GÜLBAŞ; B., ZAFER, B., YILDIZ, I., DİRİL, N., AKI-ŞENER, E., YALÇIN, İ., “Genotoxic activities and QSAR studies of some benzoxazoles and benzimidazoles”, QSAR 2006-12th International Workshop on Quantitative Structure-Activity Relationships in Enviromental Toxicology , Lyon, France, Abstract s O -67 , 8-12 May 2006.
  • 17
    AKI-ŞENER, E., YALÇIN, İ., ALPER-HAYTA, S., TEKİNER-GÜLBAŞ; B., TEMİZ ARPACI, Ö., YILDIZ, I., ALTANLAR, N., “Synthesis, antimicrobial activity and QSARs of New Benzoxazine-3-ones”, European Conference on the Reversal of Multidrug Resistance from Bacteria to Cancer Cells and Parasites, Budapest, Hungary, Abstracts OP-10, 22-25 April 2006.
  • 16
    YALÇIN, İ., AKI-ŞENER, E., YILDIZ, I., TEMİZ ARPACI, Ö., TEKİNER-GÜLBAŞ; B., “Research results incorporated on COST B16 Action from the year 2003 to 2006”, European Conference on the Reversal of Multidrug Resistance from Bacteria to Cancer Cells and Parasites, Budapest, Hungary, Abstracts OP-04, 22-25 April 2006.
  • 15
    YILDIZ, I., YALÇIN, İ., AKI-ŞENER, E., TEMİZ ARPACI, Ö., TEKİNER-GÜLBAŞ; B., “3D-QSAR Studies on Some Topoisomerase II Inhibitors” 3rd International Symposium Computational Methods In Toxicology &Pharmacology Integrating Internet Resources (CMTPI-2005), Shanghai, P.R: China, Abstract ORB-06, October 29th- November 1st, 2005.
  • 14
    AKI-ŞENER, E., YALÇIN, İ., YILDIZ, İ., TEMİZ-ARPACI, Ö., ALPER, S., ZAFER, B., “Studies on Pharmacophore Group Identification of Topoisomerase II Inhibitory Active Fused Heterocyclics Using CATALYST HipHop”, The European Cost Action B16 Symposium on Multidrug Resistance Reversal, Antalya, p19, 13-14 May, 2005.
  • 13
    LAGE, H., AKI-ŞENER, E., YALÇIN, İ., “High Antineoplastic Efficiency of Heterocyclic DNA Topoisomerase II Inhibitors in Classical and Atypical Multidrug-Resistant Cancer Cells”, The European Cost Action B16 Symposium on Multidrug Resistance Reversal, Antalya, p25, 13-14 May, 2005.
  • 12
    VARGA, A., YALÇIN, I., AKI-SENER, E., CHEREPNEV, G., FERREIRA, M.J.U., UGOCSAI, K., SGARAGLI, G., SHAH, A., MOLNAR, J. “Induction of Apoptosis and Necrosis, By Synthetic Heterocyclics and Natural Terpenoids and Phenolic Compounds”, The European Cost Action B16 Symposium on Multidrug Resistance Reversal, Antalya, p28, 13-14 May, 2005.
  • 11
    KERBOEUF, D., KOCH, C., GUEGNARD, F., TEKİNER-GULBAS, B., AKI-ŞENER, E., YALÇIN, İ., “Some Fused Heterocyclic Compounds as Anthelmintic against Haemonchus conttortus, Nematode parasite of Ruminants”, The European Cost Action B16 Symposium on Multidrug Resistance Reversal, Antalya” Abstracts 37, 13-14 May, 2005.
  • 10
    AKI-ŞENER, E., YALÇIN, İ., YILDIZ, I., TEMİZ ARPACI, Ö., ZAFER, B., TEKİNER-GÜLBAŞ; B., ALPER, S., “3D-QSAR Studies of Topoisomerase II Inhibitors Using Catalyst ” Watoc`05, Modelling Structure and Reactivity 7th Congress of the World Association of Theoretically Oriented Chemists, Cape Town, South Africa, Abstract C12-5, 16-21 January 2005.
  • 9
    YALÇIN, İ.; ŞENER, E., ARPACI-TEMİZ, Ö., Tekiner, B. “3-D QSAR of Some Antibacterial Active Heterocyclics Using the CoMSIA Method” 3rd International Symposium on Pharmaceutical Chemistry, Istanbul, Turkey, Abstracts 90, 17-19 September 2001.
  • 8
    ŞENER, E., ÖREN, İ., ARPACI-TEMİZ, YALÇIN, i., “3-D QSAR of Some Antibacterial Active Heterocyclic Compounds Using the CoMSIA Method” 6th International Symposium on Pharmaceutical Sciences, Ankara, Turkey, Abstracts 136, 27-29 September 2000.
  • 7
    ŞENER, E., ÖREN, İ., TEMİZ-ARPACI, Ö., BİNGÖL, K. K., YALÇIN, İ., QSARs of Some Novel Antibacretial Active Isosteric Heterocyclics Against Bacillus Subtilis., 2nd International Symposium on Pharmaceutical Chemistry, Ankara, Turkey, Abstract O-23, 22-24 September 1999.
  • 6
    ŞENER, E., TEMİZ, Ö., ÖREN, İ., YALÇIN, İ., ALTANLAR, N., Synthesis and QSAR Analysis of Some Novel 2,5-Disubstituted Benzoxazoles Against B. subtilis., Second International Meeting on Pharmacy and Pharmaceutical Sciences, İstanbul, Turkey, Abstracts O9, 06-09 September 1998.
  • 5
    ŞENER, E., YALÇIN, İ., SUNGUR, E., Kantitatif Yapı-Etki İlişkileri Analizi Yardımı ile Bir İlaç Etken Madde Tasarım Çalışmaları, Uluslararası Katılımlı I. Eczacılık Bilimleri Sempozyumu, Özet Kitabı S11, 21-23 Haziran 1989.
  • 4
    YALÇIN, İ., ŞENER, E., Ilaç Tasarımında Bilgisayar Uygulamalı Kantitatif Yapı-Etki Ilişkisi Tayini. Antibacteriyal Etkili Benzoksazol Türevlerinin Free-Wilson Analizi, Tıpta Bilgisayar Uygulamaları Sempozyumu II, Izmir, 26-29 Eylül 1988.
  • 3
    ŞENER, E., YALÇIN, İ., SUNGUR, E., Ilaç Tasarımında Bilgisayar Kullanımı. Antifungal Etkili Benzoksazol ve Oksazolo(4,5-b)piridin Türevlerinin Hansch Analizleri Yardımı ile Kantitatif Yapı-Etkileri , Tıpta Bilgisayar Uygulamaları Sempozyum II, Izmir, 26-29 Eylül 1988.
  • 2
    YALÇIN, İ., ŞENER, E., ÖZDEN, S., ÖZDEN, T., Gram(-) Bakterilere Karşı Antibakteriyel Etkili 2-(p-sübstitüefenil)benzoksazol Türevleri Üzerinde Kantitatif Yapı-Etki IliŞkileri, Kimya ve Kimya Mühendisliği Sempozyumu, Ankara, Özet Kitabı S:69, 17-20 Eylül 1986.
  • 1
    YALÇIN, İ., ŞENER, E., ÖZDEN, S., ÖZDEN, T., Candida albicans’a Karşı Etkili 5-Nitro-2-(p-substitüefenil)benzoksazol Türevlerinin Kantitatif Yapı-Etki Ilişkileri, Kimya ve Kimya Mühendisliği Sempozyumu, Ankara, Özet Kitabı S:68, 17-20 Eylül 1986.

Presentaciones Diapositivas

  • 26
    BOLELLİ, K., YALCIN, I., ERTAN, T., KAYNAK-ONURDAG, F., YILDIZ, I., TEMIZ-ARPACI, I., AKI-SENER, E., ABBASOGLU, U., "Synhtesis, Structure Elucidation and Microbiological Activity of Some New 2-[4-(4-Substitutedbenzamido)phenyl]benzothiazole Derivatives", Abst. P-61, 3rd International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-3), Antalya-TURKEY, October 16-21, 2007.
  • 25
    ALPER-HAYTA, S., ARISOY, M., TEMIZ-ARPACI, O., YILDIZ, I., AKI-SENER, E., KAYNAK-ONURDAG, F., "Synthesis and Antimicrobial Activity of Some New N-(2-Substitutedbenzoxazol-5-yl)-2-benzofurancarboxamides", Abst. P-11, 3rd International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-3), Antalya-TURKEY, October 16-21, 2007.
  • 24
    ARISOY, M., TEMIZ-ARPACI, O., KAYNAK-ONURDAG, F., YILDIZ, I., AKI-SENER, E., YALCIN, I., ABBASOGLU, U., "Synthesis and Antimicrobial Activity of Some Novel 2-(p-Substitutedbenzyl)-5-(2-substitutedacetamido)benzoxazole Derivatives", Abst. P-24, 3rd International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-3), Antalya-TURKEY, October 16-21, 2007.
  • 23
    ARISOY, M., TEMIZ-ARPACI, O., KAYNAK-ONURDAG, F., YILDIZ, I., AKI-SENER, E., YALCIN, I., ABBASOGLU, U., "Synthesis and Antimicrobial Activity of Some Novel N-(2-Substitutedbenzoxazol-5-yl)-2-(4-substitutedpiperazin-1-yl)acetamides", Abst. PC-29, 6th AFMC International Medicinal Chemistry Symposium (AIMECS 07), Istanbul-TURKEY, July 08-11, 2007.
  • 22
    YILDIZ, I., AKI-SENER, E., YALCIN, I., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., “3D-QSAR CoMSIA Study on Heterocyclic Topoisomerase II Inhibitors”, The 16th European Symposium on Quantitative Structure-Activity Relationships & Molecular Modelling, Mediterranean Sea, Italy, Abstract page 223, 10-17 September 2006.
  • 21
    ERTAN, T., YILDIZ, I., BOLELLI, K., TEMİZ-ARPACI, O., TEKİNER-GÜLBAŞ, B., AKI-ŞENER, E., YALÇIN, I., ABBASOGLU; U., “Synthesis and antibacterial activity of some 4-substituted-N-(2-hydroxy-5(or 6)-nitrophenyl)benzamide derivatives” International Symposium on Medicinal Chemistry Research and Development Kusadasi, Turkey, Abstract P81, September 28-October 1, 2005,.
  • 20
    TEMİZ-ARPACI, O., TEKİNER-GÜLBAŞ, B., YILDIZ, I., AKI-ŞENER, E., YALÇIN, I., ALTANLAR; N., “Synthesis and antifungal activity of some new 5-ethylsulphonyl-2-substitutedbenzoxazoles” Joint Meeting on Medicinal Chemistry, Vienna, Austria, June 20-23, 2005 Scientia Pharmaceutica Supplement 1. 73(2) S235, PO-177, 2005.
  • 19
    YILDIZ, İ., TEMİZ-ARPACI, Ö., TEKİNER-GÜLBAŞ, B., ERTAN, T., AKI-ŞENER, E., YALÇIN, I., “COMFA 3D-QSAR Studies on benzazole derivatives as eukaryotic topoisomerase II inhibitors” Joint Meeting on Medicinal Chemistry, Vienna, Austria, June 20-23, 2005 Scientia Pharmaceutica Supplement 1. 73(2) S234, PO-176, 2005.
  • 18
    AKI-ŞENER, E., YALÇIN, I., YILDIZ-ÖREN, I., TEMİZ-ARPACI, O., TEKİNER, B.; “3D-QSAR of Some Antibacterial Active Heterocyclics Using The CoMFA Method” Euro QSAR 2002, Bournemouth, Abstracts 098, 8-13 September 2002.
  • 17
    ARPACI-TEMİZ Ö., ŞENER, E., YALÇIN, İ.; TEkiner, B., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some 2,5-Disubstitutedbenzoxazole Derivatives” 3rd International Symposium on Pharmaceutical Sciences, Istanbul, Turkey, Abstracts p. 193, 17-19 September 2001.
  • 16
    ŞENER, E., ÖREN, İ., ARPACI-TEMİZ, Ö., YALÇIN, İ.; “3-D QSAR of Some Antifungal Active Heterocyclic Compounds Using the CoMSIA Method” 13th European Symposium on Quantitative Structure-Activity Relationships, QSAR 2000 Düsseldorf, Germany, Abstracts P 53, 27 August-1 September 2000.
  • 15
    ŞENER, E., ARPACI, Ö. T., ÖREN, İ., BİNGÖL, K. K., YALÇIN, İ., The QSAR Analysis of Some Novel 2-p-Substituted-phenyl-5-Substitutedcarbonylaminobenzoxazoles Against a Gram-Negative Rod., 6th International Symposium on Pharmaceutical Sciences, Ankara, Turkey., Abstracts P-147 p. 282, 27-29 June 2000.
  • 14
    YALÇIN, İ., TEKİNER, B., ÖREN, İ., ŞENER, E., TEMİZ-ARPACI, Ö., ALTANLAR, N., Synthesis and Antimicrobial Activity of Some Novel 2,6,7-Trisubstituted-2(H)-3,4-dihidro-1,4-benzoxazine Derivatives., 2nd International Symposium on Pharmaceutical Chemistry, Ankara, Turkey, Abstract P-09, 22-24 September 1999.
  • 13
    YALÇIN, İ., ÖREN, İ., TEMİZ-ARPACI, Ö., TEKİNER, B., ŞENER, E., QSARs of Some Novel Antifungal Active Isosteric Heterocyclics, 7th International Symposium on Molecular Aspects of Chemotherapy, Gdansk, Poland, Abstracts No 86, p.165, 08-11 September 1999.
  • 12
    ŞENER, E., ÖREN, İ., TEMİZ-ARPACI, Ö., BİNGÖL, K. K., YALÇIN, İ., QSARs of Some Novel Antibacterial Benzoxazoles, Benzimidazoles, Benzothiazoles and Oxazolo(4,5-b)pyridines Against S. aureus., 1999 Gordon Research Conference on Quantitative Structure-Activity Relationships, Tilton, N.H., U.S.A., 25-30 July 1999.
  • 11
    YALÇIN, İ., ŞENER, E., ÖREN, İ., Activity Contributions of Some Novel Isosteric Heterocyclics Against Nosocomial Infection Caused Gram-Negative Rod Using The Free-Wilson Analysis, 1995 Gordon Research Conference on Quantitative Structure-Activity Relationships, Tilton, N.H., U.S.A., 6-11 August 1995.
  • 10
    WOJCIECHOWSKA, J. K., MROZEK, A., YALÇIN, İ., ŞENER, E., Electronic Conditions For Antimicrobial Activity of 2,5-Disubstituted Benzoxazole Derivatives, 5th International Symposium on Molecular Aspects of Chemotherapy, Gdansk, Poland, Abstracts No 4, pg 44, 21-24 August 1995.
  • 9
    WOJCIECHOWSKA, J. K., MROZEK, A., YALÇIN, İ., ŞENER, E., Crystal and Molecular Structure of 5-Chloro-2-(p-ter-buthylphenyl)benzoxazole, 4th International Symposium on Pharmaceutical Sciences, Ankara, Abstracts P113, 27-30 Haziran 1995.
  • 8
    ŞENER, E., YALÇIN, İ., TEMİZ, Ö., ÖREN, İ., BİNGÖL, K. K., AKIN, A., UÇARTÜRK., The Synthesis and Antimicrobiological Activity of Some 2,5-Disubstituted Benzoxazole and Imidazole Derivatives, 4th International Symposium on Pharmaceutical Sciences, Ankara, Abstracts P109, 27-30 Haziran 1995.
  • 7
    ÖREN, İ., YALÇIN, İ., TEMİZ, Ö., ŞENER, E.,Determination of the Activity Contributions of Some Novel Isosteric Heterocyclics Against a Fungi Candida albicans Using The Free-Wilson Analysis, 4th International Symposium on Pharmaceutical Sciences, Ankara, Abstracts P106, 27-30 Haziran 1995.
  • 6
    YALÇIN, İ., ŞENER, E., ÖREN, İ., TEMİZ, Ö., Determination of the Activity Contributions of Some Novel Isosteric Heterocyclics against an Enteric Gram-negative Rod using the Free-Wilson Analysis, 10th European Symposium on Structure-Activity Relationships: QSAR and Molecular Modelling, Barcelona, Spain, Abstracts P-169A, 4-9 Eylül 1994.
  • 5
    ŞENER, E., TEMİZ, Ö., YALÇIN, İ., ÖREN, İ., AKIN, A., UÇARTÜRK, N., The Synthesis and Microbioloical Activity of 5-Substituted-2-(p-substituted benzyl) benzoxazoles Against Staphylococcus aureus, 3rd International Symposium on Pharmaceutical Sciences, Ankara, Abstracts P20, 15-18 Haziran 1993.
  • 4
    ŞENER, E., YALÇIN, İ., TEMIZ, Ö., ÖREN, İ., AKIN, A., The Synthesis and Microbioloical Activity of 5-Substituted-2-(p-substitutedbenzyl)benzoxazoles Against An Enteric Gram-Negative Rod, XIIth International Symposium On Medicinal Chemistry, Basel, Switzerland, Abstracts P-005. B, 13-17 Eylül 1992.
  • 3
    YALÇIN, İ., ŞENER, E., ÖREN, İ., QSARs of Some Antibacterial Active Isosteric Heterosiclic Compounds Against an Enterobacter, 9th European Symposium On Structure-Activity Relationships: QSAR and Molecular Modelling, Strasbourg, France, Abtracts p129, 07-11 Eylül 1992.
  • 2
    YALÇIN, İ., ŞENER, E., ÖREN, İ., AKIN, A., QSARs of Some Antifungal Active Benzoxazoles and Oxazolo(4,5-b)pyridines by Free-Wilson Analysis, 50th International Congress of F.I.P., Istanbul, Abstracts CS181, 03-07 Eylül 1990.
  • 1
    ŞENER, E., TURGUT, H., Bazı 5-Sübstitüe-2-(3-piridil)benzoksazol Türevlerinin Sentez, Yapı Aydınlatması ve Mikrobiyolojik Etkileri, Uluslararası Katılımlı I. Eczacılık Bilimleri Sempozyumu, Ankara, Özet Kitabı P31, 21-23 Haziran 1989.

Artículos del Congreso

  • 5
    AKI, E., YALCIN, I., YILDIZ, I., TEMIZ-ARPACI, O., BOLELLI, K., ERTAN-BOLELLI, T., DNA-Topoisomerase Inhibitory Activity of Some Heterocyclic Compounds and Their Structure-Activity Relationships", Med. Chem. Res., 19(Suppl.), S6, (2010). DOI 10.1007/s00044-010-9296-3 [texto íntegro]
  • 4
    YALCIN, I., AKI, E., YILDIZ, O., TEMIZ-ARPACI, O., “Antimicrobial Activity and Structure-Activity Relationships of Some Synthesized Benzazoles and Their Possible Metabolites”, Med. Chem. Res. 19 (Suppl. 1), S41, (2010). DOI: 10.1007/s00044-010-9296-3 [texto íntegro]
  • 3
    TEMİZ-ARPACI, Ö., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALCIN, İ., "3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method", QSAR and Molecular Modelling in Rational Design of Bioactive Molecules, Istanbul-Turkey, September 5-10, 2004, AKI-ŞENER, E., YALÇIN, İ. (Eds.), Başkent Publishing, Ankara, pp.396-398, (2006). [texto íntegro]
  • 2
    VARGA, A., AKI-SENER, E., YALCIN, I., B., CHEREPNEV, G., MOLNAR, J., “Induction of Apoptosis and Necrosis by Resistance Modifiers Benzazoles and Benzoxazines on Tumour Cell Line Mouse Lymphoma L5718 MDR+Cells”, Anticancer Research, 24(533), 3663, (2004). [texto íntegro]
  • 1
    AKBAY-YARPUZLU, A., YILDIZ, İ., TEMIZ-ARPACI, Ö., KARAGENÇ, N., AKI-ŞENER, E., YALÇIN, İ., “Adenosine Deaminase Inhibitor Activity of Some Benzoxazole, Benzimidazole, and Oxazolo(4,5-b)pyridine Derivatives”, XIII. Biotecnological Congress Proceedings Book, Çanakkale, 21-26, (2003).