Prof. Ilkay YILDIZ, Ph.D. (Former Member)

URL : http://80.251.40.59/pharmacy.ankara.edu.tr/iyildiz/
Email : iyildiz@pharmacy.ankara.edu.tr
Tel : + 90 (312) 203 30 69

Educational and Administrative Background

July 1986: B. Sc. at Ankara University, Faculty of Pharmacy
April 1989: M. Sc. degree at Ankara University Faculty of Pharmacy Department of Pharmaceutical Chemistry
July 1995: Ph.D. at University of Ankara, Faculty of Pharmacy Department of Pharmaceutical Chemistry
Supervisor: Prof. Dr. Ismail Yalcin
May 1996: Assistant Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry
November 1998: Associated Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry
March 2004: Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry

Language Background

  •  Turkish (Native Language)
  •  English (Fluent)
  •  German

Research Interests

  •  Computer-aided drug design (2D QSAR (Free-Wilson and Hansch analysis), 3D QSAR CoMFA, CoMSIA, HipHop, HypoGen, molecular modelling, conformational analysis, molecular dynamics)
  •  Computational Chemistry (Ab initio, DFT) 
  •  I am involved in some softwares such as Gaussian98, Sybyl, Macromodel, Maestro, Cerius4.10, Catalyst 4.10, APOLLO, PrGen, FlexS, SEAL, HyperChem, ChemDraw. I can use Unix, Windows 98 and Macintosh.
  •  Microbiological, Antitumoral, Antiviral, and Antioxidant activities
  •  Structure Analysis (IR, 1H NMR, Mass) and Synthesis of heterocyclic compounds
  •  HPLC

Work Experience

1986-1996: I worked at Ankara University, Faculty of Pharmacy Department of Pharmaceutical Chemistry as research assistant in various subjects given below:

  •  Instrumental methods (UV, IR, NMR, Mass)
  •  Pharmacopoeia analysis
  •  Crystallization, distillation, extraction, chromatography (TLC, Column chromatography)
  •  Qualitative and Quantitative Drug Analysis
  •  Organic Chemistry, Synthesis of drug

Since May 1996: I have been lecturing to B.Sc., M.Sc. and Ph. D. students at Ankara University Faculty of Pharmacy Department of Pharmaceutical Chemistry

Postdoctoral Studies

  • 2000-2002 Visitor professor at Emory University, Department of Chemistry (Fellowships from TUBITAK and Emory Emerson Center)
  •  DFT studies on Taxol Biosynthesis 
  •  Molecular modelling of NMDA Antagonists

Master Theses Supervised

  • Tugba ERTAN, 2005, "The Synthesis of Possible Metabolites, Structure Elucidation, Antimicrobial Activity and Molecular Modelling of Some New 2-Phenyl/benzylbenzoxazole derivatives"

Editorial Board Memberships

  •  Journal of Faculty of Pharmacy of Ankara University , Editorial Assistant (2002-Present)

Symposium and Meeting Organizations

  •  ISOPS 7th International Symposium on Pharmaceutical Sciences, Social Committee, June 24-27, 2003, Ankara.
  •  Member of the Organizing Committee of the “15th European Symposium on Quantitative Structure-Activity Relationships”, Istanbul, 05-10 September 2004.
  •  Member of the Organizing Committee of the "Workshop on Computer Aided Drug Design & Development", Istanbul-TURKEY, February 02-05, 2007.
  •  Member of the Organizing Committee of “6th AFMC International Medicinal Chemistry Symposium", Istanbul-TURKEY, July 08-11, 2007.

Memberships

  •  Ankara Chamber of Pharmacists
  •  Turkish Association of Pharmaceutical and Medicinal Chemistry
  •  Development Association of Ankara University, Faculty of Pharmacy
  •  Computer Aided Drug Design and Development Society (CADD&D Society) in Turkey

Artículos Científicos

  • 49
    ERTAN-BOLELLI, T., YILDIZ, I., OZGEN-OZGACAR, S., "Synthesis, Molecular Docking and Antimicrobial Evaluation of Novel Benzoxazole Derivatives", Med. Chem. Res., 25, 553-567 (2016). DOI: 10.1007/s00044-015-1499-1 [texto íntegro]
  • 48
    ATAEI, S., YILMAZ, S., ERTAN-BOLELLI, T., YILDIZ, I., "Generated 3D-Common Feature Hypotheses Using the HipHop Method For Developing New Topoisomerase I Inhibitors", Archiv der Pharmazie, 348(7), 498-507, (2015). DOI:10.1002/ardp.201500045 [texto íntegro]
  • 47
    AKI-YALCIN, E., ERTAN-BOLELLI, T., TASKIN-TOK, T., OZTURK, O., ATAEI, S., OZEN, C., YILDIZ, I., YALCIN, I., "Evaluation of Inhibitory Effects of Benzothiazole and 3-Amino-benzothiazolium Derivatives on DNA Topoisomerase II by Molecular Modeling Studies", SAR and QSAR in Environmental Research, 25(8), 637-649, (2014). doi:10.1080/1062936X.2014.923039 [texto íntegro]
  • 46
    ERTAN-BOLELLI, T., MUSDAL, Y., BOLELLI, K., YILMAZ, S., AKSOY, Y., YILDIZ, I., AKI-YALCIN, E., YALCIN, I., “Synthesis, Biological Evaluation of 2-Substituted-5-(4-nitrophenylsulfonamido) benzoxazoles as Human GST P1-1 Inhibitors and Description of the Binding Site Features”, ChemMedChem,9(5), 984-992, (2014). doi:10.1002/cmdc.201400010 [texto íntegro]
  • 45
    YILMAZ, S., ALTINKANAT-GELMEZ, G., BOLELLI, K., GUNESER-MERDAN, D., OVER-HASDEMIR, M. U., YILDIZ, I., AKI-YALCIN, E., YALCIN, I., “Pharmacophore Generation of 2-Substituted Benzothiazoles as AdeABC Efflux Pump Inhibitors in A. baumannii”, SAR and QSAR in Environmental Research, 25(7), 551-563, (2014). doi:10.1080/1062936X.2014.919357 [texto íntegro]
  • 44
    MARY, Y. S., JOJO, P. J., PANICKER, C. Y., VAN ALSENOY, C., ATAEI, S., YILDIZ, I., "Quantum mechanical and spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations of 2-(phenoxymethyl)benzimidazole", Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 125, 12-24, (2014). doi:10.1016/j.saa.2014.01.068 [texto íntegro]
  • 43
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., ERTAN-BOLELLI, T., YILDIZ, I., "Quantum mechanical and spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations of 5-nitro-2-phenylbenzoxazole", Journal of Molecular Structure, 1063, 16-29, (2014). Doi: 10.1016/j.molstruc.2014.01.018 [texto íntegro]
  • 42
    MARY, Y. S., JOJO, P. J., PANICKER, C. Y., VAN ALSENOY, C., ATAEI, S., YILDIZ, I., "Theoretical investigations on the molecular structure, vibrational spectra, HOMO–LUMO and NBO analysis of 5-chloro-2-((4-chlorophenoxy)methyl)benzimidazole", Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 122, 499-511, (2014). Doi: 10.1016/j.saa.2013.11.025 [texto íntegro]
  • 41
    ZILIFDAR, F., ALPER-HAYTA, S., YILMAZ, S., KAPLAN-OZEN, C., FOTO, E., AYDOGAN, Z., YILDIZ, I., AKI, E., YALCIN, I., DIRIL, N., "Genotoxic potentials and eukaryotic DNA topoisomerase I inhibitory effects of some benzoxazine derivatives", Med. Chem. Res., 23(1), 480-486, (2014). DOI: 10.1007/s00044-013-0658-5 [texto íntegro]
  • 40
    YILMAZ, S., YALCIN, I., KAYNAK-ONURDAG, F., OZGEN, S., YILDIZ, I., and AKI, E., "Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles", Croat. Chem. Acta, 86(2), 223-231, (2013). Doi: 10.5562/cca2064 [texto íntegro]
  • 39
    CAN, A., YILDIZ, I., GUVENDIK, G., "The determination of toxicities of sulphonylurea and phenylurea herbicides with quantitative structure–toxicity relationship (QSTR) studies", Environmental Toxicology and Pharmacology, 35(3), 369-379, (2013). Doi: 10.1016/j.etap.2013.02.001 [texto íntegro]
  • 38
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., YILMAZ, S., YILDIZ, I., AKI, E., "Quantum mechanical and spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations of 2-(p-nitrobenzyl) benzoxazole", Journal of Molecular Structure, 1046, 92-100, (2013). Doi: 10.1016/j.molstruc.2013.04.044 [texto íntegro]
  • 37
    KAPLAN-OZEN, C., TEKINER-GULBAS, B., FOTO, E., YILDIZ, I., DIRIL, N., AKI, E., YALCIN, I., "Benzothiazole derivatives as human DNA topoizomerase IIα inhibitors", Med. Chem. Res., 22(12), 5798-5808, (2013). DOI: 10.1007/s00044-013-0577-5 [texto íntegro]
  • 36
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., BOLELLI, K., YILDIZ, I., AKI, E., "Vibrational spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations and computational study of 5-nitro-2-(4-nitrobenzyl) benzoxazole", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 102, 99-113, (2013). doi:10.1016/j.saa.2012.09.032 [texto íntegro]
  • 35
    TASKIN, T., YILMAZ, S., YILDIZ, I., YALCIN, I., AKI, E., "Insight into eukaryotic topoisomerase II-inhibiting fused heterocyclic compounds in human cancer cell lines by molecular docking", SAR and QSAR Environmental Research, 23(3-4), 345-355, (2012). Doi:10.1080/1062936X.2012.664560 [texto íntegro]
  • 34
    MARY, Y.S., RAJU, K., ERTAN-BOLELLI, T., YILDIZ, I., NOGUEIRA, H.I.S., "FT-IR, FT-Raman, surface enhanced Raman scattering and computational study of 2-(p-fluorobenzyl)-6-nitrobenzoxazole", Journal of Molecular Structure, 1012, 22-30, (2012). doi:10.1016/j.molstruc.2011.12.042 [texto íntegro]
  • 33
    MARY, Y. S., PANICKER, C. Y., VARGHESE, H. T., RAJU, K., ERTAN-BOLELLI, T., YILDIZ, I., GRANADEIRO, C. M., NOGUEIRA, H. I. S., "Vibrational spectroscopic studies and computational study of 4-fluoro-N-(2’-hydroxy-4’-nitrophenyl)phenylacetamide", Journal of Molecular Structure, 994, 223–231, (2011). doi:10.1016/j.molstruc.2011.03.022 [texto íntegro]
  • 32
    PANICKER, C. Y., VARGHESE, H. T., USHAKUMARI, L., ERTAN, T., YILDIZ, I., GRANADEIRO, C. M., NOGUEIRA, H. I. S., MARY, Y. S., "FT-IR, FT-Raman, SERS spectra and computational calculations of 4-ethyl-N-(2'-hydroxy-5'-nitrophenyl) benzamide", J. Raman Spectroscopy 41, 381–390, (2010). DOI: 10.1002/jrs.2471 [texto íntegro]
  • 31
    PANICKER, C.Y., VARGHESE, H.T., RAJ, A., RAJU, K., ERTAN-BOLELLI, T., YILDIZ, I., TEMIZ-ARPACI, O., GRANADEIROF, C.M., NOGUEIRA, H.I.S., “IR, Raman and SERS spectra of 2-phenoxymethylbenzothiazole”, Spectrachimica Acta Part A, 74, 132–139, (2009). doi:10.1016/j.saa.2009.05.022 [texto íntegro]
  • 30
    ERTAN, T., YILDIZ, I., TEKINER-GULBAS, B., BOLELLI, K., TEMIZ-ARPACI, O., OZKAN, S., KAYNAK, F., YALCIN, I., AKI, E., “Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents”, European Journal of Medicinal Chemistry, 44, 501–510, (2009). doi:10.1016/j.ejmech.2008.04.001 [texto íntegro]
  • 29
    TEMIZ-ARPACI, Ö., YILDIZ, I., OZKAN, S., KAYNAK, F., AKI-SENER, E., YALÇIN, I., "Synthesis and biological activity of some new benzoxazoles" European Journal of Medicinal Chemistry, 43, 1423-1431, (2008). doi:10.1016/j.ejmech.2007.09.023 [texto íntegro]
  • 28
    MARY, Y.S., VARGHESE, H.T., PANICKER, C.Y., ERTAN, T., YILDIZ, I., TEMIZ-ARPACI, O., “Vibrational spectroscopic studies and ab initio calculations of 5-nitro-2-(p-fluorophenyl) benzoxazole”, Spectrachimica Acta Part A, 71, 566–571, (2008). doi:10.1016/j.saa.2007.12.041 [texto íntegro]
  • 27
    USHAKUMARI, L., VARGHESE, H.T., PANICKER, C.Y., ERTAN, T., YILDIZ, I.,“Vibrational spectroscopic studies and DFT calculations f 4-fluoro-N-(2-hydroxy-4-nitrophenyl)benzamide”, Journal of Raman Spectroscopy, 39, 1832-1839, (2008). DOI: 10.1002/jrs.2047 [texto íntegro]
  • 26
    ARISOY, M., TEMIZ-ARPACI, O., YILDIZ, I., KAYNAK-ONURDAG, F., AKI, E., YALCIN, I., ABBASOGLU, U., “Synthesis, Antimicrobial Activity and QSAR Studies of 2,5-Disubstituted Benzoxazoles”, SAR and QSAR in Environmental Research, 19(5–6), 589–612, (2008). DOI: 10.1080/10629360802348738 [texto íntegro]
  • 25
    YILDIZ, I., ERTAN, T., BOLELLI, K., TEMIZ-ARPACI, O.,YALCIN, I. AKI, E., "QSAR and Pharmacophore Analysis on Amides against Drug-Resistant S. aureus", SAR and QSAR in Environmental Research, 19(1-2), 101-113, (2008). DOI: 10.1080/10629360701844159 [texto íntegro]
  • 24
    ALPER-HAYTA, S., ARISOY, M., TEMIZ-ARPACI, Ö., YILDIZ, I., AKI, E., ÖZKAN, S., KAYNAK, F., "Synthesis, Antimicrobial Activity, Pharmacophore Analysis of Some New 2-(Substitutedphenyl/ benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles", European Journal of Medicinal Chemistry, 43(11), 2568-2578, (2008). doi:10.1016/j.ejmech.2007.12.019 [texto íntegro]
  • 23
    AMBUJAKSHAN, K.R., MADHAVAN, V.S., VARGHESE H.T., PANICKER C.Y., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., YILDIZ, I., "Vibrational Spectroscopic Studies and ab initio Calculations of 5-Methyl-2-(p-methylaminophenyl)benzoxazole", Spectrochim Acta A Mol Biomol Spectrosc., 69(3), 782-788, (2008). doi:10.1016/j.saa.2007.04.034 [texto íntegro]
  • 22
    OKSUZOGLU, E., TEKINER-GULBAS, B., ALPER, S., TEMIZ-ARPACI, O., ERTAN, T., YILDIZ, I., DIRIL, N., SENER-AKI, E., YALCIN, I., "Some Benzoxazoles and Benzimidazoles as DNA Topoisomerase I and II Inhibitors", Journal of Enzyme Inhibition and Medicinal Chemistry, 23(1), 37-42, (2008). DOI: 10.1080/14756360701342516 [texto íntegro]
  • 21
    OKSUZOGLU, E., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., EROGLU, H., SEN, G., ALPER, S., YILDIZ, I., DIRIL, N., AKI-SENER, E., YALCIN, I., "A Study on the Genotoxic Activities of Some New Benzoxazoles", Medicinal Chemistry Research, 16, 1–14, (2007). DOI 10.1007/s00044-007-9005-z [texto íntegro]
  • 20
    TEKINER-GULBAS, B., TEMIZ-ARPACI, O., OKSUZOGLU, E., EROGLU, H., YILDIZ, I., DIRIL, N., AKI-SENER, E., YALCIN, I., "QSAR of Genotoxic Active Benzazoles", SAR and QSAR in Environmental Research, 18(3-4), 251–263, (2007). DOI: 10.1080/10629360701303966 [texto íntegro]
  • 19
    ERTAN, T., YILDIZ, I., OZKAN, S., TEMIZ-ARPACI, O., KAYNAK, F., YALCIN, I., AKI-SENER, E., ABBASOGLU, U., "Synthesis and Biological Evaluation of New n-(2-Hydroxy-4(or 5)-nitro/ aminophenyl)benzamides and Phenylacetamides as Antimicrobial Agents", Bioorganic and Medicinal Chemistry, 15, 2032-2044, (2007). doi:10.1016/j.bmc.2006.12.035 [texto íntegro]
  • 18
    AKBAY-YARPUZLU, A., UGUR, Y., NAZIKOGLU, A., ASAN, E., YILDIZ, I., "Investigation of Renal Histopathological Changes Due to HIV-RT Inhibitor 2-phenoxymethyl-5-chlorobenzimidazole Administration in Rats", Hacettepe J. Biol. & Chem., 35(1), 25-30, (2007). [texto íntegro]
  • 17
    ANTO, P.L., PANICKER, C.Y., VARGHESE, H.T., PHILIP, D., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., YILDIZ, I., “Vibrational spectroscopic studies and ab initio calculations of 5-methyl-2-(p-fluorophenyl)benzoxazole”, Spectrochimica Acta Part A, 67, 744-749, (2007). Doi:10.1016/j.saa.2006.08.026 [texto íntegro]
  • 16
    TEMİZ-ARPACI, Ö., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALCIN, İ., "3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method", QSAR and Molecular Modelling in Rational Design of Bioactive Molecules, Istanbul-Turkey, September 5-10, 2004, AKI-ŞENER, E., YALÇIN, İ. (Eds.), Başkent Publishing, Ankara, pp.396-398, (2006). [texto íntegro]
  • 15
    ALPER-HAYTA, S., AKI-SENER, E., TEKINER-GULBAS, B., YILDIZ, I., TEMIZ-ARPACI, O., YALCIN, I., ALTANLAR, N., “Synthesis, Antimicrobial Activity and QSARs of New Benzoxazine-3-ones”, Eur. J. Med. Chem., 41(12), 1398-1404, (2006). [texto íntegro]
  • 14
    TEMIZ-ARPACI, O., COBAN, T., TEKINER-GULBAS, B., CAN-EKE, B., YILDIZ, İ., AKI-SENER, E., YALCIN, I., ISCAN, M., “A Study on the Antioxidant Activities of Some New Benzazole Derivatives”, Acta Biol. Hungarica, 57(2), 201-209, (2006). [texto íntegro]
  • 13
    TEKINER-GULBAS, B., TEMIZ-ARPACI, O., YILDIZ, I., AKI-SENER, E., YALCIN, I., “3D-QSAR Study on Heterocyclic Topoisomerase II Inhibitors using CoMSIA”, SAR and QSAR in Enviromental Research, 17(2), 121-132, (2006). [texto íntegro]
  • 12
    UGUR, Y., AKBAY-YARPUZLU, A., NAZIKOGLU, A., ASAN, E., YILDIZ, I., KELES, S., "Investigating Toxic Effects of the HIV-RT Inhibitor 2-Phenoxymethyl-5-chloro-benzimidazole on Rat Liver", Turkish Journal of Medical Sciences , 35(1), 5-12, (2005). [texto íntegro]
  • 11
    TEMIZ-ARPACI, O., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALÇIN, İ., “3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method”, Bioorganic&Medicinal Chemistry, 13, 6354–6359, (2005). [texto íntegro]
  • 10
    TEMİZ-ARPACI, O., ÖZDEMİR, A., YALÇIN, İ., YILDIZ, İ., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some 5-[2-(Morpholin-4-yl)acetamido] and/or 5-[2-(4-Substituted piperazin-1-yl)acetamido]-2-(p-substituted phenyl)benzoxazoles", Arch. Pharm. Chem. Life Sci., 338, 105-111, (2005). [texto íntegro]
  • 9
    YILDIZ-OREN, İ., TEKINER-GULBAŞ, B., TEMİZ-ARPACI, Ö., YALÇIN, İ., AKI-SENER, E., "Quantitative Structure-Activity Relationships using Comparative Molecular Field Analysis Studies on 2-(p-Substitutedbenzyl)-5-(substituted carbonylamino)benzaoxazoles as Antibacterial Agents against Staphylococcus aureus", Asian Journal of Chemistry, 16(3-4), 1359-1366, (2004). [texto íntegro]
  • 8
    ÖREN-YILDIZ, İ., TEKİNER-GULBAŞ, B., YALÇIN, İ., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of New 2-[p-Substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles”, Arch. Pharm. Pharm. Med. Chem, 337, 402-410, (2004). [texto íntegro]
  • 7
    PLEMPER, R.K., ERLANDSON, K.J., LAKDAWALA, A.S., SUN, A., PRUSSIA, A., BOONSOMBAT, J., AKI-ŞENER, E., YALÇIN, İ., YILDIZ, İ., TEMİZ-ARPACI, Ö., TEKİNER, B. P., LIOTTA, D., SNYDER, J.P., COMPANS, R.W., “A Target Site for Template-Based Design of Measles Virus Entry Inhibitors”, PNAS, 101(15), 5628-5633, (2004). [texto íntegro]
  • 6
    ÖREN-YILDIZ, İ., YALÇIN, İ., AKI-ŞENER, E., UCARTURK, N., “Synthesis and Structure-Activity Relationships of New Antimicrobial Active Multisubstituted Benzazole Derivatives”, European Journal of Medicinal Chemistry, 39, 291-298, (2004). [texto íntegro]
  • 5
    PINAR, A., YURDAKUL, P., YILDIZ, İ., TEMİZ-ARPACI, Ö., AÇAN, N.L., AKI-ŞENER, E., YALÇIN, İ.,”Some Fused Heterocyclic Compounds as Eukaryotic Topoisomerase II Inhibitors”, Biochemical and Biophysical Research Communications, 317, 670-674, (2004). [texto íntegro]
  • 4
    YILDIZ-ÖREN, i., AKI-ŞENER, E., ERTAŞ, C., TEMİZ-ARPACI, Ö., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological activity of Some Substituted N-(2-hydroxy-4-nitrophenyl)benzamides and phenylacetamides as Possible Metabolites of Antimicrobial Active Benzoxazoles”, Turk J Chem., 28, 441-449, (2004). [texto íntegro]
  • 3
    YALÇIN, İ., TEKİNER, B.P., ÖREN-YILDIZ, İ., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some Novel 2,6,7-trisubstituted-2H-3,4-dihydro-1,4-benzoxazin-3-one Derivatives”, Indian Journal of Chemistry, 42B, 905-909, (2003). [texto íntegro]
  • 2
    AKBAY-YARPUZLU, A., YILDIZ, İ., TEMIZ-ARPACI, Ö., KARAGENÇ, N., AKI-ŞENER, E., YALÇIN, İ., “Adenosine Deaminase Inhibitor Activity of Some Benzoxazole, Benzimidazole, and Oxazolo(4,5-b)pyridine Derivatives”, XIII. Biotecnological Congress Proceedings Book, Çanakkale, 21-26, (2003).
  • 1
    LANKIN, D.C., GRUNEWALD, G.L., ROMERO, F.A., YILDIZ-OREN, I., SNYDER, J.P., “The NH---FC Dipole Orientation Effect for Pendant Exocylic CH(2)F”, Organic Letters, 4(21), 3557-3560, (2002). [texto íntegro]

Presentaciones Orales

  • 8
    YILDIZ, I., ALPER, S., ERTAN, T., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., AKI-SENER, E., YALCIN, I., "Molecular Modeling Studies on Some Eucaryotic Topoisomerase II Enzyme Inhibitor Fused Heterocyclic Compounds", 6th AFMC International Medicinal Chemistry Symposium, Istanbul-TURKEY, July 08-11, 2007.
  • 7
    PINAR, A., YURDAKUL, P., TEMİZ-ARPACI, O., TEKİNER-GÜLBAŞ, B., YILDIZ, I., AKI-ŞENER, E., YALÇIN, İ., İLERİ, O., “Eukaryotic Topoisomerase II activity of some novel fused heterocyclic compounds”, 31st FEBS Congress, İstanbul, Turkey, 24-29 June 2006.
  • 6
    TEMİZ ARPACI, Ö., ÖKSÜZOĞLU, e., TEKİNER-GÜLBAŞ; B., ZAFER, B., YILDIZ, I., DİRİL, N., AKI-ŞENER, E., YALÇIN, İ., “Genotoxic activities and QSAR studies of some benzoxazoles and benzimidazoles”, QSAR 2006-12th International Workshop on Quantitative Structure-Activity Relationships in Enviromental Toxicology , Lyon, France, Abstract s O -67 , 8-12 May 2006.
  • 5
    AKI-ŞENER, E., YALÇIN, İ., ALPER-HAYTA, S., TEKİNER-GÜLBAŞ; B., TEMİZ ARPACI, Ö., YILDIZ, I., ALTANLAR, N., “Synthesis, antimicrobial activity and QSARs of New Benzoxazine-3-ones”, European Conference on the Reversal of Multidrug Resistance from Bacteria to Cancer Cells and Parasites, Budapest, Hungary, Abstracts OP-10, 22-25 April 2006.
  • 4
    YALÇIN, İ., AKI-ŞENER, E., YILDIZ, I., TEMİZ ARPACI, Ö., TEKİNER-GÜLBAŞ; B., “Research results incorporated on COST B16 Action from the year 2003 to 2006”, European Conference on the Reversal of Multidrug Resistance from Bacteria to Cancer Cells and Parasites, Budapest, Hungary, Abstracts OP-04, 22-25 April 2006.
  • 3
    YILDIZ, I., YALÇIN, İ., AKI-ŞENER, E., TEMİZ ARPACI, Ö., TEKİNER-GÜLBAŞ; B., “3D-QSAR Studies on Some Topoisomerase II Inhibitors” 3rd International Symposium Computational Methods In Toxicology &Pharmacology Integrating Internet Resources (CMTPI-2005), Shanghai, P.R: China, Abstract ORB-06, October 29th- November 1st, 2005.
  • 2
    AKI-ŞENER, E., YALÇIN, İ., YILDIZ, İ., TEMİZ-ARPACI, Ö., ALPER, S., ZAFER, B., “Studies on Pharmacophore Group Identification of Topoisomerase II Inhibitory Active Fused Heterocyclics Using CATALYST HipHop”, The European Cost Action B16 Symposium on Multidrug Resistance Reversal, Antalya, p19, 13-14 May, 2005.
  • 1
    AKI-ŞENER, E., YALÇIN, İ., YILDIZ, I., TEMİZ ARPACI, Ö., ZAFER, B., TEKİNER-GÜLBAŞ; B., ALPER, S., “3D-QSAR Studies of Topoisomerase II Inhibitors Using Catalyst ” Watoc`05, Modelling Structure and Reactivity 7th Congress of the World Association of Theoretically Oriented Chemists, Cape Town, South Africa, Abstract C12-5, 16-21 January 2005.

Presentaciones Diapositivas

  • 8
    BOLELLİ, K., YALCIN, I., ERTAN, T., KAYNAK-ONURDAG, F., YILDIZ, I., TEMIZ-ARPACI, I., AKI-SENER, E., ABBASOGLU, U., "Synhtesis, Structure Elucidation and Microbiological Activity of Some New 2-[4-(4-Substitutedbenzamido)phenyl]benzothiazole Derivatives", Abst. P-61, 3rd International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-3), Antalya-TURKEY, October 16-21, 2007.
  • 7
    ALPER-HAYTA, S., ARISOY, M., TEMIZ-ARPACI, O., YILDIZ, I., AKI-SENER, E., KAYNAK-ONURDAG, F., "Synthesis and Antimicrobial Activity of Some New N-(2-Substitutedbenzoxazol-5-yl)-2-benzofurancarboxamides", Abst. P-11, 3rd International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-3), Antalya-TURKEY, October 16-21, 2007.
  • 6
    ARISOY, M., TEMIZ-ARPACI, O., KAYNAK-ONURDAG, F., YILDIZ, I., AKI-SENER, E., YALCIN, I., ABBASOGLU, U., "Synthesis and Antimicrobial Activity of Some Novel 2-(p-Substitutedbenzyl)-5-(2-substitutedacetamido)benzoxazole Derivatives", Abst. P-24, 3rd International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-3), Antalya-TURKEY, October 16-21, 2007.
  • 5
    ARISOY, M., TEMIZ-ARPACI, O., KAYNAK-ONURDAG, F., YILDIZ, I., AKI-SENER, E., YALCIN, I., ABBASOGLU, U., "Synthesis and Antimicrobial Activity of Some Novel N-(2-Substitutedbenzoxazol-5-yl)-2-(4-substitutedpiperazin-1-yl)acetamides", Abst. PC-29, 6th AFMC International Medicinal Chemistry Symposium (AIMECS 07), Istanbul-TURKEY, July 08-11, 2007.
  • 4
    YILDIZ, I., AKI-SENER, E., YALCIN, I., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., “3D-QSAR CoMSIA Study on Heterocyclic Topoisomerase II Inhibitors”, The 16th European Symposium on Quantitative Structure-Activity Relationships & Molecular Modelling, Mediterranean Sea, Italy, Abstract page 223, 10-17 September 2006.
  • 3
    ERTAN, T., YILDIZ, I., BOLELLI, K., TEMİZ-ARPACI, O., TEKİNER-GÜLBAŞ, B., AKI-ŞENER, E., YALÇIN, I., ABBASOGLU; U., “Synthesis and antibacterial activity of some 4-substituted-N-(2-hydroxy-5(or 6)-nitrophenyl)benzamide derivatives” International Symposium on Medicinal Chemistry Research and Development Kusadasi, Turkey, Abstract P81, September 28-October 1, 2005,.
  • 2
    TEMİZ-ARPACI, O., TEKİNER-GÜLBAŞ, B., YILDIZ, I., AKI-ŞENER, E., YALÇIN, I., ALTANLAR; N., “Synthesis and antifungal activity of some new 5-ethylsulphonyl-2-substitutedbenzoxazoles” Joint Meeting on Medicinal Chemistry, Vienna, Austria, June 20-23, 2005 Scientia Pharmaceutica Supplement 1. 73(2) S235, PO-177, 2005.
  • 1
    YILDIZ, İ., TEMİZ-ARPACI, Ö., TEKİNER-GÜLBAŞ, B., ERTAN, T., AKI-ŞENER, E., YALÇIN, I., “COMFA 3D-QSAR Studies on benzazole derivatives as eukaryotic topoisomerase II inhibitors” Joint Meeting on Medicinal Chemistry, Vienna, Austria, June 20-23, 2005 Scientia Pharmaceutica Supplement 1. 73(2) S234, PO-176, 2005.

Artículos del Congreso

  • 3
    AKI, E., YALCIN, I., YILDIZ, I., TEMIZ-ARPACI, O., BOLELLI, K., ERTAN-BOLELLI, T., DNA-Topoisomerase Inhibitory Activity of Some Heterocyclic Compounds and Their Structure-Activity Relationships", Med. Chem. Res., 19(Suppl.), S6, (2010). DOI 10.1007/s00044-010-9296-3 [texto íntegro]
  • 2
    TEMİZ-ARPACI, Ö., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALCIN, İ., "3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method", QSAR and Molecular Modelling in Rational Design of Bioactive Molecules, Istanbul-Turkey, September 5-10, 2004, AKI-ŞENER, E., YALÇIN, İ. (Eds.), Başkent Publishing, Ankara, pp.396-398, (2006). [texto íntegro]
  • 1
    AKBAY-YARPUZLU, A., YILDIZ, İ., TEMIZ-ARPACI, Ö., KARAGENÇ, N., AKI-ŞENER, E., YALÇIN, İ., “Adenosine Deaminase Inhibitor Activity of Some Benzoxazole, Benzimidazole, and Oxazolo(4,5-b)pyridine Derivatives”, XIII. Biotecnological Congress Proceedings Book, Çanakkale, 21-26, (2003).